Professor, Dept. of Veterinary Microbiology and Preventive Medicine
Research Interests / Areas of Expertise:
Our research focuses on bacterial diseases of production animals, including their effects on animal health, public health and food safety. The long-term goal of one of our projects is to establish the molecular basis of virulence and antimicrobial resistance of avian pathogenic Escherichia coli (APEC), the causative agent of colibacillosis, an economically devastating problem for the poultry industry. Establishing the molecular basis of APEC virulence and resistance should lead to more rational approaches for future colibacillosis control strategies. Additionally, we are exploring the possible link between extraintestinal pathogenic E. coli (ExPEC) of food animals, such as APEC, and human extraintestinal diseases, such as urinary tract infection, septicemia, and meningitis.
Education & Certifications:
D.V.M.: University of Georgia, Athens, GA, 1988.
M.S.: Medical Microbiology, University of Georgia, Athens, GA, 1989.
Ph.D.: Medical Microbiology, University of Georgia, Athens, GA, 1992.
Selected Publications:
Gibbs, P.S., Maurer, J.J., Nolan, L.K., and Wooley, R.E. 2003. Prediction of Chicken Embryo Lethality with the Avian Escherichia coli Traits Complement Resistance, Colicin V Production, and Presence of the Increased Serum Survival Gene Cluster (iss). Avian Dis. 47:370-379.
*Horne, S.M., Goplin, J., and Nolan, L.K. 2004. Cloning and Sequence Analysis of cnf-1 from Virulent Bovine and Mink Escherichia coli Isolates. Vet Res Comm. 28:103-112.
*Johnson, T.J., Skyberg, J., and Nolan, L.K. 2004. Multiple Antimicrobial Resistance Region of a Putative Virulence Plasmid from an Escherichia coli Isolate Incriminated in Avian Colibacillosis. Avian Dis. 48: 351-360.
Balasubramanian,S., Panigrahi, S., Logue, C., Marchello, M., Doetkott, C., Gu, H., and Nolan, L.K. 2004. Spoilage Identification of Beef Using an Electronic Nose System. Trans Am Soc Agric Eng 47: xxx-xxx.
*Rodriguiz-Siek, K.E., Giddings, C.W., Fakhr, M., Doetkott, C., Johnson, T.J., and Nolan, L.K. 2004. Defining an APEC Pathotype. Accepted with revisions by Vet Res. (9/04)
Johnson, T.J., Siek, K., Skyberg, J., Doetkott, C., and Nolan, L.K. Plasmid-Linked Virulence among Avian Pathogenic Escherichia coli. As part of the Proceedings of the Biannual Meeting of the International Plasmid Biology Society, Corfu, Greece, September 2004. Accepted by Plasmid (10/05)
Leadership:
Executive Chair, College of Veterinary Medicine, Iowa State University, Ames, Iowa, 2006-
Chair, Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, 2003-
Interim Chair, Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, 2004-2005.
Director, Great Plains Institute of Food Safety, North Dakota State, 1999-2003
Member, Wellness Center Advisory Board, NDSU, 2001-2003
Member, North Dakota EPSCoR Steering Committee, 2001-2002
Member, Center for Advanced Technology Transfer and Traineeships Advisory Board, NDSU, 2002-2003
Member, NDSU Research Foundation Advisory Board, 2002-2003
Ad hoc Reviewer, USDA NRICG Program, 1993, 1994, 2000, 2001, 2002
Member, Board of Scientific Reviewers, American Journal of Veterinary Research, 1994 1996
Ad hoc Reviewer, Journal of American Veterinary Medical Association, 1994, 1995, 1997, 1998, 2001
Ad hoc Reviewer, Plant Disease, 1996, 1997
Ad hoc Reviewer, Veterinary Research Communications, 1997, 1999, 2000, 2001
Ad hoc Reviewer, American Journal of Veterinary Research, 1999, 2000
Member, Program Committee, National Alliance for Food Safety, 1st Annual Meeting, Washington, D.C., 1999
Chair, Food and Environmental Safety Session, Conference of Research Workers in Animal Disease, Chicago, IL, 1999, 2000 (Co-Chair in 2001)
Member, Editorial Review Board, Animal Health Research Reviews, 1999-2000
Member, FDA Food Animal Grants Review Panel (Microbiological Hazards Associated with the Food Animal Production Environment), CVM-FDA, Rockville, MD, 2000
Section Editor, Food and Environmental Safety Section, Animal Health Research Reviews, 2000-
Member, FDA-CVM's Veterinary Medicine Advisory Committee, 2003-2006
Honors & Awards:
Preferred AG Instructor, College of Agriculture Student Activities Council, NDSU, 1995
Mortar Board Preferred Professor, NDSU, 1996, 1997, 1998, 1999
Commendation, College of Agriculture Excellence in Teaching, Early Career, NDSU, 1996
Member, Phi Kappa Phi, 1998-
Mary McCannel Gunkelman 10th Annual Recognition Award, NDSU, 1998
University-Wide Odney Teaching Award, NDSU, 1999
Outstanding Academic Advisor, College of Agriculture, Mortar Board
National Honor Society, NDSU, 1999
Professorship, Walter F. and Verna Gehrts Presidential Professor, NDSU, 2001-2003
Distinguished Educator of the Year, Blue Key National Honor Society, NDSU, 2001
Memberships:
American Veterinary Medical Association, 1984-
American Association of Avian Pathologists, 1991-
American Society for Microbiology, 1992-
Research Workers in Animal Disease, 1993-
International Society of Plasmid Biology, 2004-
